Southampton will be hoping to make it back-to-back wins they host Arsenal on Thursday.
After a slightly sluggish start, the Saints quickly got back into the rhythm of things with a comprehensive 3-0 victory at Norwich on Friday.
The Southampton attack was spearheaded superbly by the likes of Danny Ings, Nathan Redmond and Stuart Armstrong, who all got on the scoresheet.
Meanwhile, Arsenal have had a nightmare return with two defeats from two games, losing 3-0 at Manchester City last Wednesday and 2-1 at Brighton on Sunday thanks to a last-minute winner for the Seagulls.
The Gunners have also been hit hard with injuries after Pablo Mari and Granit Xhaka came off in Manchester, while Bernd Leno was stretchered off with a nasty looking knee issue at Brighton.
This will give Ralph Hasenhuttl some hope of beating Mikel Arteta’s side and drawing level on points with their opponents who currently have 40, three clear of Saints’ tally of 37.
This was the fixture that secured Hasenhuttl’s first victory in charge of Southampton with a memorable 3-2 triumph last season.
In his pre-match press conference, the Austrian revealed a clean bill of health ahead of Thursday’s clash with Moussa Djenepo the only absentee through suspension.
Here’s how we predict the side to line up:
