Southampton host Manchester United in the early kick-off this Saturday looking for their third consecutive win in all competitions after wins away to Brighton and Fulham respectively.
Manchester United, on the other hand, are looking to bounce back from their home defeat to Crystal Palace last weekend.
Both sides come into the fixture with some significant first-team injuries. Southampton will be without Nathan Redmond, Moussa Djenepo and Michael Obafemi, who all suffered injuries in the midweek Carabao Cup win at Craven Cottage.

Manchester United will be without Luke Shaw and Antony Martial, who picked up injuries in the defeat to Crystal Palace, while Diogo Dalot, Eric Bailly and Timothy Fosu-Mensah still remain sidelined.
The two fixtures between these two sides last season produced two entertaining games and plenty of goals, as a 2-2 draw at St Mary’s and a 3-2 defeat at Old Trafford saw Manchester United take four points from Saints last season.
This combined XI is selected of the players who will be fit and available ahead of the game on Saturday lunchtime. It will line up in a 4-3-3 formation, which can also be adapted into a 4-2-3-1.
Without further ado, let’s see who makes this combined XI.




