Saints kick off the 2017/18 campaign as they host Swansea City at St Mary’s Stadium.
With new arrivals Jan Bednarek and Mario Lemina looking to enter the fray, Mauricio Pellegrino’s side will be keen to make the best start possible to the season, and aim to take the spoils on Saturday.
Southampton have had a mixed pre-season, recording victories over Saint-Etienne and Sevilla, draws against St Gallen and Brentford, whilst losing at the hands of FC Augsburg.
Swansea’s unbeaten pre-season tour of America was complemented by a resounding win over Sampdoria, however a setback against Barnet at the start of pre-season was Paul Clement’s only worry.
Tammy Abraham and Roque Mesa could feature for the Swans, who managed to escape relegation last season.
With both sides firmly in the transfer limelight, neither Saints captain Virgil van Dijk or Swansea catalyst Gylfi Sigurdsson will make an appearance for their respective sides, as their futures are yet to be decided.
So, here are five things to look out for in Saints’ Premier League curtain raiser!